The MR BIO study aims to learn how tumours and normal tissues change during a course of radiotherapy. To do this, we look closely at the MRI scans taken at each treatment session on the MR‑Linac — a radiotherapy machine that has a built‑in MRI scanner. This allows us to take high‑quality images while you are being treated, helping us target the tumour more precisely and better protect the surrounding healthy tissues.

Researchers believe that changes seen on MRI scans, along with biological information from blood, tissue or urine samples, could help predict how well treatment works. Understanding these changes may help improve radiotherapy for future patients.

Who can take part

All patients having their radiotherapy treatment on the MR‑Linac at The Christie may be invited to join, no matter what type of tumour they are being treated for.

What taking part involves

• You will continue to receive your standard radiotherapy treatment, exactly as planned for your condition.
• In addition, we will ask you to provide:
  • Weekly blood and urine samples during your radiotherapy
  • One set of samples at your first follow‑up visit
• After radiotherapy finishes, you will stay on your usual follow‑up schedule with your oncology team.
  
  These improved MRI techniques will then be used when imaging patients during treatment.