83results. Page 9of 83.

ID:14
Study Name:MOMENTUM
Iras Number:259162
Study Type:Observational
Anatomical Region:Other
Disease Site:Multi
Study Status:Open
Study disease site icon
Site Location:
The Christie NHS Foundation Trust
Wilmslow Road, Manchester, M20 4BX
The Christie NHS Foundation Trust
Full Study Title:
The Multiple OutcoMe EvaluatioN of radiation Therapy Using the MR-Linac Study
Research Summary:

MOMENTUM is an international research project designed to help us better understand and improve a new type of radiotherapy machine called the MR‑Linac. This machine combines MRI imaging with radiation treatment, allowing doctors to see the tumour more clearly during therapy and adapt treatment in real time.

The study involves patients treated on MR‑Linac machines at several hospitals in the UK, the Netherlands, the United States and Canada. By collecting information from patients who have imaging or treatment on the MR‑Linac, researchers can learn how to use this technology in the safest and most effective way

What the study aims to do

MOMENTUM collects information before, during and after treatment. This helps researchers:

  • Improve how the MR‑Linac works, including both the imaging and treatment processes.
  • Assess the safety and practicality of new treatment approaches, such as adapting treatment based on daily changes in the tumour.
  • Create a long-term data repository, allowing doctors and researchers to follow patients over time and learn from their outcomes.
  • Guide future research, helping to develop better tools, software and treatment methods for MR‑Linac radiotherapy.
  • Understand treatment results, including side effects, tumour control, and patient survival across different cancer types.
  • Build a library of MRI images, which helps refine treatment planning and improve adaptive radiotherapy in the future.
    The study is run through the MR‑Linac Consortium—an international partnership of hospitals, universities and industry experts working together to advance MRI‑guided radiotherapy.

Patients will be asked to complete Quality of Life questionnaires and allow their treatment data (scans and doses) to be collected and anonymised. Optional extra images are another part of the study which patients may take part in should they wish.  

Date Site Open:
OCT
04
2019
Study End Date:
JAN
01
2028
Randomisation
Additional Appointments
Link to NIHR Database: Not provided